Why is the ratio of free psa to total psa low?

The ratio of dispersed PSA to total PSA is slightly lower, and the actual ratio and the actual value of total PSA need to be established to make the determination. If the total PSA is between 4-10ng/L and the ratio of dispersed PSA level to total PSA is <0.16, considering the possibility of prostate malignant tumors, it is recommended to conduct follow-up consultation or prostate biopsy.

If the ratio of scattered PSA to total PSA is >0.16, prostate malignant tumors are not considered, and regular follow-up can be carried out. However, if the total PSA level is >10ng/L or above, regardless of the ratio of scattered PSA to total PSA, follow-up consultation or prostate biopsy is required. Malignant tumors of the prostate may exist, so the diagnosis needs to be based on the actual standard value, and a magnetic resonance imaging of the prostate is required to further assist the diagnosis.

A low ratio of dispersed PSA to total PSA should be considered as a higher possibility of prostate cancer. It is recommended that everyone do a prostate color ultrasound examination to determine whether there is hypoechoic content in the jugular vein. ； Do an MRI of the male prostate to look for hypoechoic nodules in the jugular vein band of the male prostate. ； Perform a digital anal examination of the male prostate to check whether the prostate is hard and whether there are masses. If there are hardness and masses, we recommend prostate biopsy for all men. It is recommended to perform 14-17 needle punctures to effectively screen whether there is the possibility of prostate cancer. Puncture biopsy is the best way to diagnose.

When clinically examining prostate-specific antigen, it is mainly used to assess whether elderly patients have the risk of prostate cancer. If the test result of prostate-specific antigen is between 4-10ng/mL, it is the gray value range for diagnosis of prostate cancer. Therefore, the ratio of dispersed to total prostate-specific antigen should be evaluated to assess the risk of prostate cancer. If the ratio is <0.15, there may be a higher risk of prostate cancer ； If the ratio is >0.25, the risk of prostate cancer is low. If it is close to the two, it is necessary to conduct digital anal examination of the prostate and MRI of the prostate area. If necessary, it is also necessary to conduct partial prostate biopsy to determine the pathological type to determine whether there is a risk of prostate cancer. Therefore, when the ratio is low, patients should undergo further testing to rule out prostate cancer.