New Health Experts Q&A Men’s Health

What to do if there are blisters on the glans penis

Asked by:Boudreau

Asked on:Apr 11, 2026 06:30 AM

Answers:1 Views:422
  • Centaur Centaur

    Apr 11, 2026

    Blisters on the glans penis may be related to factors such as genital herpes, allergic reactions, balanitis, contact dermatitis, friction injuries, etc., and can be treated through local cleaning, antiviral treatment, anti-allergic drugs, antibiotic ointments, surgical intervention, etc. It is recommended to seek medical treatment promptly for a clear diagnosis and avoid self-medication or scratching the affected area.

    1. Partial cleaning

    Gently clean the glans and the inside of the foreskin with warm water every day and avoid using irritating lotions. Keep the perineum dry and breathable, and choose pure cotton underwear to reduce friction. If the blisters have not burst, they can be covered with sterile gauze for protection after cleaning. Broken blisters need to be prevented from secondary infection, and sexual intercourse should be temporarily avoided after cleaning.

    2. Antiviral treatment

    Genital herpes requires the use of antiviral drugs such as acyclovir cream and penciclovir cream as directed by your doctor. If relapses occur or symptoms are severe, oral administration of valacyclovir hydrochloride tablets may be required. The disease is contagious, sexual contact should be avoided during treatment, and partners need to be checked simultaneously.

    3. Anti-allergic drugs

    For blisters that occur after contact with allergenic substances such as condoms and detergents, topical hydrocortisone butyrate cream can be used to relieve itching and swelling. Oral loratadine tablets can help reduce systemic allergic reactions. Recording the history of exposure to allergens can help doctors determine the cause of the disease and conduct a patch test if necessary.

    4. Antibiotic ointment

    For blisters caused by bacterial balanitis, mupirocin ointment or compound polymyxin B ointment can be applied. When combining white secretions, the secretions need to be collected for pathogen culture. People with diabetes are more susceptible to such infections and need to monitor their blood sugar levels.

    5. Surgical intervention

    For those with recurrent inflammation caused by phimosis or redundant foreskin, circumcision may be considered after the acute phase subsides. Postoperative soaking in potassium permanganate solution is used to promote healing. When huge blisters affect urination, the doctor may perform sterile puncture drainage and red light irradiation treatment.

    You should avoid scratching or popping blisters on your own daily to prevent the spread of infection. Sexual life is suspended during treatment, and spouses or sexual partners need to be screened for sexually transmitted diseases. Choose loose and breathable cotton underwear to reduce local friction. The diet should be light and limit the intake of spicy foods. If the blisters are accompanied by fever, swollen inguinal lymph nodes, or the ulcer does not heal for a long time, immediate follow-up examination is required to rule out the possibility of malignant lesions.

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