prostate hyperplasia

In fact, prostatic hyperplasia is a relatively mild prostate disease compared with other prostate diseases. However, after suffering from prostatic hyperplasia, patients will feel obvious urination difficulties. Especially middle-aged men have a very high chance of suffering from prostate hyperplasia, so middle-aged men should take some methods to prevent prostate hyperplasia in their daily lives. At this time, it is also necessary to understand the causes of prostatic hyperplasia.

Causes of prostate hyperplasia

1. The role of sex hormones

The existence of functional testicles is a necessary condition for the occurrence of prostatic hyperplasia, and its incidence increases with age. Testosterone is the sex hormone in the male body. Testosterone is converted into dihydrotestosterone with stronger action through the action of 5α-reductase in the prostate. Dihydrotestosterone can promote the increase of prostate cells, causing the prostate volume to gradually increase. Inhibiting the action of 5α-reductase in the body reduces the production of dihydrotestosterone, resulting in a reduction in the number of prostate cells, thereby reducing the size of the prostate. Some people also believe that there is a synergistic effect of estrogen and androgens in the development and development of prostatic hyperplasia, and changes in the balance of estrogen and androgens are the cause of prostatic hyperplasia.

2. Prostate cells reawaken for the embryo

Studies have found that the initial pathological change of prostatic hyperplasia, that is, the formation of hyperplastic nodules, only occurs in an area that accounts for 5% to 10% of the prostate gland, that is, the transition zone close to the prostatic sphincter and the periurethral area located inside this sphincter. The initial change of prostatic hyperplasia nodules is the proliferation of glandular tissue, that is, the original glandular ducts form new branches and grow into the appendages. In the proximal stroma, a new framework structure (i.e., a nodule) is formed after complex re-branching. McNeal proposed the embryonic reawakening theory of prostatic hyperplasia based on the basic characteristic of embryonic development, which is the formation of new structures. He believed that the formation of prostatic hyperplasia nodules is the result of a certain prostate stromal cell spontaneously transforming into an embryonic development state during the growth process.

3. Polypeptide growth factors

Polypeptide growth factors are a type of polypeptide substances that regulate cell differentiation and growth. Studies have shown that peptide growth factors can directly regulate the growth of prostate cells, while sex hormones only play an indirect role. Polypeptide growth factors currently found to play an important role in the occurrence of prostatic hyperplasia mainly include: epidermal growth factor (EGF), transforming growth factors α and β, fibroblast growth factor (FGF), insulin-like growth factor-I, etc. Among them, basic fibroblast growth factor (bFGF) has been confirmed to have the mitotic effect of promoting almost all cells in human prostate homogenate, and its role in the pathogenesis of prostatic hyperplasia is increasingly valued.

4. Lifestyle

There is a positive correlation between obesity and prostate volume, that is, the more fat, the larger the prostate volume. Although the conclusions are inconsistent, some existing research suggests that nutrients can influence the risk of BPH and LUTS. Increased intake of total energy and total protein, as well as increased intake of fat, milk and dairy products, red meat, grains, poultry, and starch, can potentially increase the risk of prostate hyperplasia and prostate surgery; while vegetables, fruits, polyunsaturated fatty acids, linoleic acid, and vitamin D can potentially reduce the risk of prostate hyperplasia.

What are the health care methods for prostate hyperplasia?

1. Use drugs with caution. Some drugs can aggravate dysuria and cause acute urinary retention in high doses. These drugs mainly include atropine, belladonna tablets, ephedrine tablets, isoproterenol, etc. These drugs should be used with caution. In recent years, it has been found that calcium blockers and verapamil can promote prolactin secretion, weaken the contractility of the detrusor, and aggravate dysuria. Therefore, certain drugs should be used with caution or preferably not used.

2. Treat diseases that cause prostatic hyperplasia in a timely manner. Prostatitis, cystitis, and urethrolithiasis should be treated promptly and thoroughly. This is also one of the health care measures for prostatic hyperplasia.

3. Massage the lower abdomen. How to take good care of prostate hyperplasia? Massage the lower abdomen and press the Qiguan, Guanyuan and other points under the navel, which is beneficial to the recovery of bladder function. Massage with a little pressure after urinating can promote bladder emptying and reduce residual fluid.

4. Prevent colds. From late autumn to early spring, the weather is unpredictable, and cold often aggravates the condition of prostate hyperplasia. Therefore, patients must pay attention to cold protection and prevent colds and upper respiratory tract infections.

5. Absolutely avoid alcohol. Drinking alcohol can cause congestion and edema of the prostate and bladder neck and induce urinary retention.

6. Eat less spicy food. Spicy and irritating food can not only cause congestion of sexual organs, but also worsen the symptoms of hemorrhoids and constipation, compress the prostate, and aggravate difficulty in urination.